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  • bsm-63171R叉頭蛋白O4重組兔單抗

    This gene encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving this gene on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been fou

    更新時間:2025-03-05
    型號:bsm-63171R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:41
  • bsm-63170R磷酸化樁蛋白Paxillin重組兔單抗

    Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase

    更新時間:2025-03-05
    型號:bsm-63170R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:49
  • bsm-63169R組蛋白去乙?;?0重組兔單抗

    The enzymes responsible for the reversible acetylation/ deacetylation process of histones are histone acetyltransferases (HATs) and histone deacetylases (HDACs), respectively. HATs act as transcriptional coactivators and HDACs are part of transcriptional corepressor complexes. Mammalian HDACs can be divided into three classes according to sequence homology. Class I consists of the yeast Rpd3 like proteins HDAC1, HDAC2, HDAC3, and HDAC8. Class II consists of the yeast Hda1 like proteins HDAC1

    更新時間:2025-03-05
    型號:bsm-63169R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:41
  • bsm-63168R磷酸化原癌基因c-Jun重組兔單抗

    C-jun (Oncoprotein C-jun) is a component of the transcription factor AP-1 that binds and activates transcription at TRE/AP-1 elements and appears to be a major downstream target of the SAPK/JNK signaling pathway. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73. Extracellular signals including growth factors, transforming oncoproteins and UV irradiation stimulate phosphorylation of c-Jun at Ser63/73 and activate c-Jun dependent transcription. Mutatio

    更新時間:2025-03-05
    型號:bsm-63168R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:38
  • bsm-63167R絲裂原活化蛋白激酶MKK3/MKK6重組兔單抗

    The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kina

    更新時間:2025-03-05
    型號:bsm-63167R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:37
  • bsm-63166R信號轉(zhuǎn)導(dǎo)與轉(zhuǎn)錄激活因子1重組兔單抗

    The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. The protein encoded by this gene can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of

    更新時間:2025-03-05
    型號:bsm-63166R
    廠商性質(zhì):生產(chǎn)廠家
    瀏覽量:37
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